cosieWrapper          package:oneChannelGUI          R Documentation

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_D_e_s_c_r_i_p_t_i_o_n:

     COSIE is a function that for a given set of exon arrays corrects
     for the observed bias and improves  the detection of alternative
     splicing. It adjusts splicing indices for exons, especially for
     those that belong  to differentially expressed genes. For this
     adjustment, COSIE uses parameters that are specific for each
     probeset  which were trained from a large number of published exon
     arrays. The downside of this approach is that such parameters 
     cannot be estimated for all probesets on the microarray. Based on
     our training set, COSIE corrects 95.1 percent  of the probesets.
     Separate parameter files are provided for both the full and core
     sets, including all  probesets that are linked to transcripts. We
     recommend the use of the core set that was also used in the cited
     study below.  The full set is not as well characterized.

_U_s_a_g_e:

     cosieWrapper()

_A_u_t_h_o_r(_s):

     Gaidatzis et al. Nucleic Acids Research, 2009, 1

_S_e_e _A_l_s_o:

     cosieHscore, cosieMmcore, cosieHsfull, cosieMmfull

