Package: bridge
Title: Bayesian Robust Inference for Differential Gene Expression
Version: 1.0.1
Author: Raphael Gottardo
Description: Test for differentially expressed genes with microarray
        data. This package can be used with both cDNA microarrays or
        Affymetrix chip. The packge fits a robust Bayesian
        hierarchical model for testing for differential expression.
        Outliers are modeled explicitly using a $t$-distribution. The
        model includes an exchangeable prior for the variances which
        allow different variances for the genes but still shrink
        extreme empirical variances. Our model can be used for testing
        for differentially expressed genes among multiple samples, and
        can distinguish between the different possible patterns of
        differential expression when there are three or more samples.
        Parameter estimation is carried out using a novel version of
        Markov Chain Monte Carlo that is appropriate when the model
        puts mass on subspaces of the full parameter space.
Maintainer: Raphael Gottardo <raph@stat.washington.edu>
Depends: R (>= 1.9.0), rama
License: GPL version 2 or newer
Packaged: Wed May 18 03:37:40 2005; biocbuild
Built: R 2.1.0; i386-pc-mingw32; 2005-05-19 03:11:14; windows
