findComplexBP {y2hStat} | R Documentation |
This function takes in the adjacency matrix of y2h data and some in silico interactome, ISI, (as the incidence matrix of the bi-partite graph). For each complex of the interactome, we can generate a new adjacency matrix with only those constituent members indexing the rows and columns (if they appear in the indexing set of the original adjacency matrix). We can then study the y2h relationship on each protein complex.
findComplexBP(amMat, ISI)
amMat |
The adjacency matrix of y2h data |
ISI |
The incidence matrix of the bi-partite graph of an in silico interactome |
NB - amMat need not be y2h data, but any data set which is binary and can be represented as an adjacency matrix.
A list of matrices. Each matrix will have the indexing set of its row and columns restricted to the intersection of the constituent members of each protein complex of the ISI with those proteins in the original adjacency matrix.
T Chiang